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Article

Identification of an interleukin-15alpha receptor-binding site on human interleukin-15.

The Journal of biological chemistry - 4 Jun 2004

Bernard Jérôme, Harb Catherine, Mortier Erwan, Quéméner Agnès, Meloen Rob H, Vermot-Desroches Claudine, Wijdeness John, van Dijken Peter, Grötzinger Joachim, Slootstra Jerry W, Plet Ariane, Jacques Yannick

Abstract excerpt

To identify the epitopes in human interleukin-15 (IL-15) that are responsible for binding to the interleukin-15 receptor alpha chain, antibody and receptor mapping by peptide scanning and site-directed mutagenesis was used. By using peptide scanning, we identified four regions in IL-15. The first...

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Identifiers

PMID: 15039446
DOI: 10.1074/jbc.M312458200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15039446-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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