Mutagenesis of specificity and toxicity regions of a Bacillus thuringiensis protoxin gene.

doi:10.1128/jb.177.14.4059-4065.1995

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Article

Mutagenesis of specificity and toxicity regions of a Bacillus thuringiensis protoxin gene.

Journal of bacteriology - 1 Jul 1995

Aronson A I, Wu D, Zhang C

Abstract excerpt

Two different 30-nucleotide regions of the cryIAc insecticidal protoxin gene from Bacillus thuringiensis were randomly mutagenized. One region was within one of seven amphipathic helices believed to be important for the formation of ion channels. There was no loss of toxicity for three test insec...

Topics

Amino Acid Sequence
Animals
Bacillus thuringiensis
Bacillus thuringiensis Toxins
Bacterial Proteins
Bacterial Toxins
Biological Assay
Endotoxins
Escherichia coli
Genes, Bacterial
Genetic Variation
Hemolysin Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Larva

Membrane Proteins

Molecular Sequence Data

Moths

Mutagenesis

Protein Binding

Source

Open in PubMed Open full text

Identifiers

PMID: 7608080
DOI: 10.1128/jb.177.14.4059-4065.1995
PMCID: PMC177137

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7608080-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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