Dynamics of unconditionally deleterious mutations: Gaussian approximation and soft selection.

Abstract excerpt

This paper studies the influence of two opposite forces, unidirectional unconditionally deleterious mutations and directional selection against them, on an amphimictic population. Mutant alleles are assumed to be equally deleterious and rare, so that homozygous mutations can be ignored. Thus, a genotype is completely described by its value with respect to a quantitative trait chi, the number of mutations it...

Topics

• Alleles
• Animals
• Genotype
• Models, Genetic
• Mutation
• Normal Distribution
• Reproduction
• Selection, Genetic