The role of thyroid hormone and promoter diversity in the regulation of nuclear encoded mitochondrial proteins.

doi:10.1016/0925-4439(95)00014-u

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Article

The role of thyroid hormone and promoter diversity in the regulation of nuclear encoded mitochondrial proteins.

Biochimica et biophysica acta - 24 May 1995

Nelson B D, Luciakova K, Li R, Betina S

Abstract excerpt

Thyroid hormone regulates the in vivo expression of a selected set of rat nuclear genes encoding mitochondrial inner membrane proteins. Certain mRNAs, such as that for cytochrome c1, are increased as much as 20-50-fold, while others, such as core protein 1 of Complex III and the F1-ATPase beta-subunit do not respond. The promoter region of human cytochrome c1 also supports thyroid hormone induction of a reporter...

Topics

3T3 Cells
Animals
Base Sequence
Blotting, Northern
Cell Division
Cell Nucleus
Cytochromes c1
Gene Expression Regulation
Genetic Variation
Humans
Hypothyroidism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Macromolecular Substances

Membrane Proteins

Mice

Mitochondria

Mitochondria, Liver

Molecular Sequence Data

Oxidative Phosphorylation

Source

Open in PubMed

Identifiers

PMID: 7599231
DOI: 10.1016/0925-4439(95)00014-u

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7599231-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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