Article
Cellular response to conditional expression of hepatitis C virus core protein in Huh7 cultured human hepatoma cells
1 May 2002
Abstract excerpt
Data suggesting that the hepatitis C virus (HCV) core protein influences normal cellular processes remain controversial. To determine the effects of core on cellular gene expression in hepatocytes, we developed a human hepatoma (Huh7)-derived cell line with tightly regulated core expression under the control of a tetracycline-regulated promoter. Cells expressing core did not have impaired proliferative abilities....
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