Article
Thyroid hormone modifies mitochondrial phenotype by increasing protein import without altering degradation.
The American journal of physiology - 1 Dec 1998
Craig E E, Chesley A, Hood D A
Abstract excerpt
The mitochondrial phenotype within cardiac muscle cells is dramatically altered by thyroid hormone. We report here that this can be accounted for, in part, by modifications in the rate of mitochondrial protein import. The import of matrix-localized precursor proteins malate dehydrogenase (MDH) and ornithine carbamoyltransferase was augmented, whereas the insertion of the outer membrane protein Bcl-2 was...
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