Most African-American patients with rheumatoid arthritis do not have the rheumatoid antigenic determinant (epitope)

doi:10.7326/0003-4819-123-3-199508010-00004

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Article

Most African-American patients with rheumatoid arthritis do not have the rheumatoid antigenic determinant (epitope)

Annals of internal medicine - 1 Aug 1995

McDaniel D O, Alarcón G S, Pratt P W, Reveille J D

Abstract excerpt

OBJECTIVE: To evaluate the relation between the presence of the "rheumatoid epitope," defined by a sequence motif in the HLA-DRB1 alleles, and disease severity in African-American patients with rheumatoid arthritis. DESIGN: Cross-sectional study. SETTING: Rheumatology outpatient clinics at two university medical centers. PATIENTS: 86 African-American patients with rheumatoid arthritis (66 seropositive and 20...

Topics

Adult
Aged
Alleles
Amino Acid Sequence
Arthritis, Rheumatoid
Black People
Cross-Sectional Studies
DNA Probes
Female
Genotype
HLA-DR Antigens
HLA-DRB1 Chains

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Immunodominant Epitopes

Male

Middle Aged

Molecular Sequence Data

Nucleic Acid Hybridization

Source

Open in PubMed

Identifiers

PMID: 7598299
DOI: 10.7326/0003-4819-123-3-199508010-00004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7598299-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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