Article
The positively acting amdA gene of Aspergillus nidulans encodes a protein with two C2H2 zinc-finger motifs.
Molecular microbiology - 1 Mar 1995
Lints R, Davis M A, Hynes M J
Abstract excerpt
Semi-dominant mutations in the amdA gene lead to elevated expression of the gene encoding acetamidase, amdS. These mutations also cause constitutive expression of the acetate-inducible gene, aciA. In the amdS 5' regulatory region, two cis-acting mutations, amdl66 and amdl666, have been isolated which specifically affect amdA activation of amdS. These mutations are a duplication and a triplication of an 18 bp...
Topics
- Acetates
- Alleles
- Amidohydrolases
- Amino Acid Sequence
- Aspergillus nidulans
- Base Sequence
- Chromosome Walking
- Cloning, Molecular
- DNA-Binding Proteins
- Fungal Proteins
- Gene Expression Regulation, Fungal