Article
Identification of functional regions of the positively acting regulatory gene amdR from Aspergillus nidulans.
Molecular microbiology - 1 Oct 1992
Parsons L M, Davis M A, Hynes M J
Abstract excerpt
The amdR (intA) regulatory gene of Aspergillus nidulans encodes a 765-amino-acid polypeptide which determines the omega-amino acid induction of at least five structural genes. The AmdR polypeptide contains a potential Zn(II)2Cys6 DNA-binding motif which has been shown to be present in the N-terminal region of a large number of fungal activator proteins. In vitro mutagenesis of the fourth cysteine of this motif...
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