Molecular characterization of mutants of the acetate regulatory gene facB of Aspergillus nidulans.

doi:10.1006/fgbi.1997.1007

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Article

Molecular characterization of mutants of the acetate regulatory gene facB of Aspergillus nidulans.

Fungal genetics and biology : FG & B - 1 Oct 1997

Todd R B, Kelly J M, Davis M A, Hynes M J

Abstract excerpt

The facB gene of Aspergillus nidulans encodes a DNA binding transcriptional activator required for growth on acetate as a sole carbon source. FacB contains N-terminal GAL4-like Zn(II)2Cys6 (or C6 zinc) binuclear cluster DNA binding and leucine zipper-like heptad repeat motifs and central and C-terminal acidic alpha-helical regions. facB recessive loss of function mutants are deficient in acetate induction of...

Topics

Acetates
Alleles
Amidohydrolases
Amino Acid Sequence
Aspergillus nidulans
Enzyme Induction
Enzyme Stability
Escherichia coli
Fungal Proteins
Genes, Fungal
Molecular Sequence Data
Mutation
Recombinant Fusion Proteins
Sequence Analysis, DNA
Sequence Deletion
Temperature
Trans-Activators
Zinc Fingers

Source

Open in PubMed

Identifiers

PMID: 9367656
DOI: 10.1006/fgbi.1997.1007

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