Article
Glioblastoma multiforme in four siblings: a cytogenetic and molecular genetic study.
Journal of neuro-oncology - 1 Jan 1995
Dirven C M, Tuerlings J, Molenaar W M, Go K G, Louis D N
Abstract excerpt
The familial occurrence of gliomas, in the absence of well-defined neurological tumor syndromes such as the neurofibromatoses, is uncommon. We present a family of ten children in which the four eldest suffered from gliomas. Three of these siblings had histologically verified glioblastoma multifor...
Topics
- Adult
- Brain Neoplasms
- Female
- Genes, p53
- Glioblastoma
- Humans
- Intestinal Neoplasms
- Karyotyping
- Lymphoma, Non-Hodgkin
- Magnetic Resonance Imaging
- Male
- Mutation
- Neoplasms, Second Primary
- Pedigree