Article
Glioblastoma multiforme in four siblings: a cytogenetic and molecular genetic study.
Journal of neuro-oncology - 1 Jan 1995
Dirven C M, Tuerlings J, Molenaar W M, Go K G, Louis D N
Abstract excerpt
The familial occurrence of gliomas, in the absence of well-defined neurological tumor syndromes such as the neurofibromatoses, is uncommon. We present a family of ten children in which the four eldest suffered from gliomas. Three of these siblings had histologically verified glioblastoma multiforme, and one patient also had an intestinal non-Hodgkin's lymphoma, but there were no stigmata or family history of a...
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