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Article

Varicella-zoster virus induces apoptosis in cell culture

1 Nov 1995

Abstract excerpt

Apoptosis is an active mechanism of cell death which can be initiated in response to various stimuli including virus infections. In this work, we demonstrate that lytic infection by varicella-zoster virus (VZV), a human herpesvirus, is characterized by nuclear fragmentation of DNA into oligonucleosomal fragments and by chromatin condensation. In vitro, VZV-induced cell death is actually mediated by apoptosis. The...

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PMID: 7595398
DOI: 10.1099/0022-1317-76-11-2875

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