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Inhibition of apoptosis prevents West Nile virus induced cell death

29 May 2007

Abstract excerpt

BACKGROUND: West Nile virus (WNV) infection can cause severe meningitis and encephalitis in humans. Apoptosis was recently shown to contribute to the pathogenesis of WNV encephalitis. Here, we used WNV-infected glioma cells to study WNV-replication and WNV-induced apoptosis in human brain-derived cells. RESULTS: T98G cells are highly permissive for lytic WNV-infection as demonstrated by the production of...

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PMID: 17535425
DOI: 10.1186/1471-2180-7-49

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