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Chandipura Virus Induces Neuronal Death through Fas-Mediated Extrinsic Apoptotic Pathway

12 Sept 2013

Abstract excerpt

Chandipura virus (CHPV; genus Vesiculovirus, family Rhabdoviridae) is an emerging tropical pathogen with a case fatality rate of 55 to 75% that predominantly affects children in the age group of 2 to 16 years. Although it has been established as a neurotropic virus causing encephalitis, the molecular pathology leading to neuronal death is unknown. The present study elucidates for the first time the mechanism of...

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PMID: 24027318
DOI: 10.1128/jvi.01864-13

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