Review: a major component of radiation action: interference with intracellular control of differentiation.

doi:10.1080/09553009514551321

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Article

Review: a major component of radiation action: interference with intracellular control of differentiation.

International journal of radiation biology - 1 Oct 1995

von Wangenheim K H, Peterson H P, Schwenke K

Abstract excerpt

If genetic lesions were the sole reason of damage induced by ionizing radiation, an increase in the number of identical chromosome sets (polyploidy) may be expected to have a radioprotective effect. This effect is evident in terminally differentiated tissues when the reduction in remaining life s...

Topics

Animals
Cell Differentiation
Humans
Interphase
Mitochondria
Mitosis
Mutation
Neoplasms
Polyploidy
Radiation Tolerance

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