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Article

High- and low-LET induced chromosome damage in human lymphocytes: a time-course of aberrations in metaphase and interphase

1 Jan 2001

Abstract excerpt

PURPOSE: To investigate how cell-cycle delays in human peripheral lymphocytes affect the expression of complex chromosome damage in metaphase following high- and low-LET radiation exposure. MATERIALS AND METHODS: Whole blood was irradiated in vitro with a low and a high dose of 1 GeV u(-1) iron particles, 400MeV u(-1) neon particles or y-rays. Lymphocytes were cultured and metaphase cells were collected at...

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PMID: 11236924
DOI: 10.1080/0955300001003760

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