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Article

The Biosynthesis of Cyclopropanated Mycolic Acids in Mycobacterium tuberculosis

1 Nov 1995

Abstract excerpt

The major mycolic acid produced by Mycobacterium tuberculosis contains two cis-cyclopropanes in the meromycolate chain. The gene whose product cyclopropanates the proximal double bond was cloned by homology to a putative cyclopropane synthase identified from the Mycobacterium leprae genome sequencing project. This gene, named cma2, was sequenced and found to be 52% identical to cma1 (which cyclopropanates the...

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PMID: 7592990
DOI: 10.1074/jbc.270.45.27292

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The Biosynthesis of Cyclopropanated Mycolic Acids in Mycobacterium tuberculosisPMID 7592990Read ↗

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