Article
Functional diversity of C2 domains of synaptotagmin family. Mutational analysis of inositol high polyphosphate binding domain.
The Journal of biological chemistry - 3 Nov 1995
Fukuda M, Kojima T, Aruga J, Niinobe M, Mikoshiba K
Abstract excerpt
Synaptotagmins I and II are inositol high polyphosphate series (inositol 1,3,4,5-tetrakisphosphate (IP4), inositol 1,3,4,5,6-pentakisphosphate, and inositol 1,2,3,4,5,6-hexakisphosphate) binding proteins, which are thought to be essential for Ca(2+)-regulated exocytosis of neurosecretory vesicles...
Topics
- Amino Acid Sequence
- Animals
- Antibodies
- Base Sequence
- Binding Sites
- Calcium-Binding Proteins
- Cloning, Molecular
- Conserved Sequence
- DNA Primers
- Genetic Variation
- Inositol Phosphates
- Kinetics
- Membrane Glycoproteins
- Mice
- Molecular Sequence Data
- Multigene Family
- Mutagenesis, Site-Directed
- Nerve Tissue Proteins