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Article

Structural features in lipoprotein lipase necessary for the mediation of lipoprotein uptake into cells.

Journal of lipid research - 1 Nov 1995

Krapp A, Zhang H, Ginzinger D, Liu M S, Lindberg A, Olivecrona G, Hayden M R, Beisiegel U

Abstract excerpt

Lipoprotein lipase (LpL) has been shown to mediate the uptake of lipoproteins into cells. The uptake is initiated by binding of LpL to cell surface proteoglycans and to the low density lipoprotein (LDL) receptor-related protein. This ability of LpL is independent of catalytic activity and depends on the intact dimeric structure of the lipase and functional residues in the C-terminal domain. The goal of this study...

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PMID: 8656074

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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