Article
Papulacandin B resistance in budding and fission yeasts: isolation and characterization of a gene involved in (1,3)beta-D-glucan synthesis in Saccharomyces cerevisiae.
Journal of bacteriology - 1 Oct 1995
Castro C, Ribas J C, Valdivieso M H, Varona R, del Rey F, Duran A
Abstract excerpt
Papulacandin B, an antifungal agent that interferes with the synthesis of yeast cell wall (1,3)beta-D-glucan, was used to isolate resistant mutants in Schizosaccharomyces pombe and Saccharomyces cerevisiae. The resistance to papulacandin B always segregated as a recessive character that defines a...
Topics
- Aminoglycosides
- Anti-Bacterial Agents
- Antifungal Agents
- Base Sequence
- Cell-Free System
- Cloning, Molecular
- Drug Resistance, Microbial
- Genes, Fungal
- Glucans
- Glucosyltransferases
- Membrane Proteins
- Molecular Sequence Data
- Mutagenesis
- Peptides, Cyclic