cps1+, a Schizosaccharomyces pombe gene homolog of Saccharomyces cerevisiae FKS genes whose mutation confers hypersensitivity to cyclosporin A and papulacandin B.

doi:10.1128/jb.179.24.7653-7662.1997

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Article

cps1+, a Schizosaccharomyces pombe gene homolog of Saccharomyces cerevisiae FKS genes whose mutation confers hypersensitivity to cyclosporin A and papulacandin B.

Journal of bacteriology - 1 Dec 1997

Ishiguro J, Saitou A, Durán A, Ribas J C

Abstract excerpt

The Schizosaccharomyces pombe cps1-12 (for chlorpropham supersensitive) mutant strain was originally isolated as hypersensitive to the spindle poison isopropyl N-3-chlorophenyl carbamate (chlorpropham) (J. Ishiguro and Y. Uhara, Jpn. J. Genet. 67:97-109, 1992). We have found that the cps1-12 muta...

Topics

Amino Acid Sequence
Aminoglycosides
Anti-Bacterial Agents
Antifungal Agents
Base Sequence
Cell Wall
Cloning, Molecular
Cyclosporine
Drug Resistance, Microbial
Echinocandins
Fungal Proteins
Genes, Fungal
Glucosyltransferases
Membrane Proteins
Molecular Sequence Data

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Identifiers

PMID: 9401022
DOI: 10.1128/jb.179.24.7653-7662.1997
PMCID: PMC179726

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9401022-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Mutation

Phenotype

Saccharomyces cerevisiae