Article
Sensitivity of somatic mutations in human umbilical cord blood to maternal environments.
Environmental and molecular mutagenesis - 1 Jan 1995
Manchester D K, Nicklas J A, O'Neill J P, Lippert M J, Grant S G, Langlois R G, Moore D H, Jensen R H, Albertini R J, Bigbee W L
Abstract excerpt
To assess the potential effect of maternal environments on human embryonic/fetal somatic mutation, we measured the frequencies of hypoxanthine-guanine phosphoribosyltransferase (HPRT, hprt gene), mutant T lymphocytes (Mf), and glycophorin A (GPA) variant erythrocytes (Vf) of both allele-loss (phi...
Topics
- Adult
- Analysis of Variance
- Cloning, Molecular
- Colorado
- DNA
- Environmental Pollutants
- Erythrocytes
- Ethnicity
- Female
- Fetal Blood
- Gene Deletion
- Glycophorins
- Humans
- Hypoxanthine Phosphoribosyltransferase
- Infant, Newborn