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Article

Sensitivity of somatic mutations in human umbilical cord blood to maternal environments.

Environmental and molecular mutagenesis - 1 Jan 1995

Manchester D K, Nicklas J A, O'Neill J P, Lippert M J, Grant S G, Langlois R G, Moore D H, Jensen R H, Albertini R J, Bigbee W L

Abstract excerpt

To assess the potential effect of maternal environments on human embryonic/fetal somatic mutation, we measured the frequencies of hypoxanthine-guanine phosphoribosyltransferase (HPRT, hprt gene), mutant T lymphocytes (Mf), and glycophorin A (GPA) variant erythrocytes (Vf) of both allele-loss (phi/N) and allele-loss-and-duplication (N/N) phenotypes in umbilical cord blood. The mean hprt Mf (1.40 +/- 1.11 x 10(-6),...

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Identifiers

PMID: 7588645
DOI: 10.1002/em.2850260304

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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