Article
[Studies on the cell models of differentiation reversal phenotypes of human rhabdomyosarcoma].
Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 Jul 1995
Lin Z, Zhang Z, Han Y
Abstract excerpt
We have observed the features of malignant phenotypes in human rhabdomyosarcoma RD cells. These cells exhibited high growth rate, aberrant relation between cell proliferation and myogenic terminal differentiation, blockage of myofibrillogenesis, inhibition of gap junctional intercellular communication (GJIC) and inhibition of transcriptional expression of gap junction gene, connexin 43 (Cx43). By utilization of...
Topics
- Cell Transformation, Neoplastic
- Connexin 43
- Gap Junctions
- Gene Expression
- Genes, myc
- Genes, ras
- Humans
- Phenotype
- Rhabdomyosarcoma
- Transcription, Genetic
- Transfection
