Apolipoprotein B-38.9 does not associate with apo[a] and forms two distinct HDL density particle populations that are larger than HDL.

Abstract excerpt

We have identified a new truncated apolipoprotein B (apoB) that provides insights into the interaction of apoB with apo[a] and with lipids. Both total and LDL-cholesterol were below the 5th percentile in the proband; Lp[a] was 28 mg/dl. Four other affected individuals were identified in this kind...

Topics

• Aged
• Amino Acid Sequence
• Apolipoproteins A
• Apolipoproteins B
• Base Sequence
• Centrifugation, Density Gradient
• Chromatography, Gel
• Gene Deletion
• Humans
• Lipoproteins, HDL
• Male
• Molecular Sequence Data
• Mutation
• Particle Size
• Pedigree
• Recombinant Proteins