Apolipoprotein B gene mutations affecting cholesterol levels.

Abstract excerpt

In the past 5 years, many different mutations in the apolipoprotein (apo) B gene have been described that affect plasma cholesterol levels. More than 20 different mutations in the apoB gene have been shown to cause familial hypobetalipoproteinaemia, a condition characterized by abnormally low pla...

Topics

• Apolipoproteins B
• Cholesterol
• Gene Expression Regulation
• Genetic Variation
• Humans
• Hypobetalipoproteinemias
• Mutation