Article
Bromocriptine in the treatment of alcoholics with the D2 dopamine receptor A1 allele.
Nature medicine - 1 Apr 1995
Lawford B R, Young R M, Rowell J A, Qualichefski J, Fletcher B H, Syndulko K, Ritchie T, Noble E P
Abstract excerpt
Various types of alcoholics have been described and heredity has been shown to be involved in some of these types. An important role of the mesolimbic dopamine system has been suggested in the reinforcing effects of alcohol and recent molecular genetic studies are implicating the gene for the D2 dopamine receptor (DRD2) in alcoholism. In a double-blind study, bromocriptine, a DRD2 agonist, or placebo was...
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