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Article

A minimal conditioning approach to achieve stable multilineage mouse plus rat chimerism.

Transplant immunology - 1 Jun 1995

Abou el-Ezz A Y, Boggs S S, Johnson P C, Li H, Patrene K D, Itskowitz M S, Kaufman C L, Ildstad S T

Abstract excerpt

Transplantation of untreated rat bone marrow into lethally irradiated (950 cGy) mouse recipients results in durable xenogeneic (rat-->mouse) chimerism and confers donor-specific transplantation tolerance for subsequent xenografts. The purpose of the present study was to characterize the minimal dose of total body irradiation (TBI) which would allow engraftment of rat bone marrow in mouse recipients. We report...

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PMID: 7582911
DOI: 10.1016/0966-3274(95)80036-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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