Article
Expression of prostaglandin E receptor subtypes in bone: expression of EP2 in bone development.
Bone - 1 Jul 1995
Kasugai S, Oida S, Iimura T, Arai N, Takeda K, Ohya K, Sasaki S
Abstract excerpt
Prostaglandin (PG) E2 displays physiological and pharmacological action in various tissues including bone. It increases intracellular Ca, and stimulates or inhibits cAMP production through the PGE receptor subtypes EP1, EP2, and EP3, respectively. These receptor subtypes have been recently cloned. In the present study, we investigate the expression of these receptor subtypes in bone tissue. RT-PCR revealed that...
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