Article
Characterization and prevalence of a polymorphism in the 3' untranslated region of cytochrome P4501A1 in cancer-prone Atlantic tomcod.
Archives of biochemistry and biophysics - 10 Sept 1995
Roy N K, Kreamer G L, Konkle B, Grunwald C, Wirgin I
Abstract excerpt
Atlantic tomcod (Microgadus tomcod) from the cancer-prone Hudson River population exhibit a genetic polymorphism in the cytochrome P4501A (CYP1A) gene which is evidenced in Northern blot analyses by a truncated transcript and in Southern blot analyses by a deletion in the variant allele. To initi...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Base Sequence
- Carcinoma, Hepatocellular
- Cytochrome P-450 Enzyme System
- DNA Primers
- DNA, Complementary
- Fish Diseases
- Fishes
- Fresh Water
- Humans
- Liver Neoplasms
- Molecular Sequence Data
- North America
- Polymorphism, Genetic
- Sequence Homology, Amino Acid
- Species Specificity