Article
Genetic diversity at an oncogene locus and in mitochondrial DNA between populations of cancer-prone Atlantic tomcod.
Biochemical genetics - 1 Oct 1990
Wirgin I I, D'Amore M, Grunwald C, Goldman A, Garte S J
Abstract excerpt
It has been reported that Atlantic tomcod (Microgadus tomcod) from the Hudson River exhibit an extremely high incidence of liver tumors. More than 90% of spawning 2-year-old fish display hepatocellular carcinomas. In contrast, representatives of this species from a relatively pristine environment show a much lower incidence of tumors. Genomic DNA and mitochondrial DNA (mtDNA) were isolated from tomcod from the...
Topics
- Animals
- Biological Evolution
- DNA, Mitochondrial
- Fish Diseases
- Fishes
- Genes, abl
- Genetic Variation
- Genetics, Population
- Liver Neoplasms
- Maine
- New York