Article
A WD-domain protein that is associated with and phosphorylated by the type II TGF-beta receptor.
Nature - 12 Oct 1995
Chen R H, Miettinen P J, Maruoka E M, Choy L, Derynck R
Abstract excerpt
Transforming growth factor-beta (TGF-beta) is the prototype for a family of extracellular polypeptides that affect cell proliferation and differentiation, and tissue morphogenesis. TGF-beta signalling is mediated by two types of serine/threonine kinase receptors, the type I and II receptors, whic...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cell Line
- Eukaryotic Initiation Factor-3
- Humans
- Mice
- Molecular Sequence Data
- Mutation
- Phosphorylation
- Plasmids
- Protein Binding
- Protein Serine-Threonine Kinases
- Proteins
- Receptor, Transforming Growth Factor-beta Type II
- Receptors, Transforming Growth Factor beta
- Recombinant Proteins
- Transforming Growth Factor beta
