Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A WD-domain protein that is associated with and phosphorylated by the type II TGF-beta receptor.

Nature - 12 Oct 1995

Chen R H, Miettinen P J, Maruoka E M, Choy L, Derynck R

Abstract excerpt

Transforming growth factor-beta (TGF-beta) is the prototype for a family of extracellular polypeptides that affect cell proliferation and differentiation, and tissue morphogenesis. TGF-beta signalling is mediated by two types of serine/threonine kinase receptors, the type I and II receptors, which are able to form a heteromeric complex. No cytoplasmic proteins that associate with these receptors in vivo, or are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Base Sequence
Share to Cell Line

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Molecular Sequence Data

Share to Mutation

Share to Plasmids

Share to Recombinant Proteins

Source

Identifiers

PMID: 7566156
DOI: 10.1038/377548a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A WD-domain protein that is associated with and phosphorylated by the type II TGF-beta receptor.PMID 7566156Read ↗

The Type II Transforming Growth Factor (TGF)-β Receptor-interacting Protein TRIP-1 Acts as a Modulator of the TGF-β ResponseSemantic proximity Read ↗

The type II TGF-beta receptor signals diverse responses in cooperation with the type I receptor.Semantic proximity Read ↗

The TGF-β signaling modulators TRAP1/TGFBRAP1 and VPS39/Vam6/TLP are essential for early embryonic development.Semantic proximity Read ↗

The TGF-beta family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase.Semantic proximity Read ↗

Smads are the central component in transforming growth factor-beta signaling.Semantic proximity Read ↗

The novel type I serine-threonine kinase receptor Alk8 binds TGF-beta in the presence of TGF-betaRII.Semantic proximity Read ↗

Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor.Semantic proximity Read ↗

TAK1 participates in c-Jun N-terminal kinase signaling during Drosophila development.Semantic proximity Read ↗

Molecular evolution of a developmental pathway: phylogenetic analyses of transforming growth factor-beta family ligands, receptors and Smad signal transducers.Semantic proximity Read ↗

Novel Function of a Transcription Factor WT1 in Regulating Decidualization in Human Endometrial Stromal Cells and Its Molecular MechanismSemantic proximity Read ↗

Functional association of TGF-β receptor II with cyclin BSemantic proximity Read ↗

The TGF-beta--Smad network: introducing bioinformatic tools.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.