Article
The TGF-beta--Smad network: introducing bioinformatic tools.
Trends in genetics : TIG - 1 Feb 2002
Kloos Dorothee U, Choi Claudia, Wingender Edgar
Abstract excerpt
The TGF-beta superfamily is an important class of intercellular signalling molecule, including TGF-beta and bone morphogenetic proteins. Intracellular signalling cascades triggered by these molecules eventually activate transcription factors of the Smad family, which then regulate expression of their respective target genes. This article will discuss the TGF-beta--Smad signalling networks and how these processes...
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