Article
Enhanced expression of novel CD57+CD8+ LAK cells from cats infected with feline immunodeficiency virus.
Journal of leukocyte biology - 1 Oct 1995
Zhao Y, Gebhard D, English R, Sellon R, Tompkins M, Tompkins W
Abstract excerpt
As a model for lymphokine-activated killer (LAK) function in HIV infection, we studied LAK cells in cats infected with feline immunodeficiency virus (FIV), which causes an acquired immunodeficiency syndrome. Peripheral blood mononuclear cells cultured in concanavalin A and interleukin-2 developed LAK cytotoxicity against chronically FIV-infected CrFK cells and acutely infected CD4+ lymphocytes but not uninfected...
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