Article
Reversal of feline leukemia virus infection by adoptive transfer of lectin/interleukin-2-activated lymphocytes, interferon-alpha, and zidovudine.
Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy - 1 Jul 1993
Zeidner N S, Mathiason-DuBard C K, Hoover E A
Abstract excerpt
Previous experimental studies utilizing human recombinant interferon-alpha-2b (IFN alpha-2b) alone or with zidovudine (AZT) to treat established feline leukemia virus (FeLV) infection resulted in a significant reduction in circulating virus throughout a 49-day treatment period. However, the anti-FeLV effect of IFN alpha was limited by the production of IFN alpha-neutralizing antibodies detected 7 weeks after the...
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