Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Feline immunodeficiency virus envelope glycoprotein mediates apoptosis in activated PBMC by a mechanism dependent on gp41 function.

Virology - 20 Dec 2004

Garg Himanshu, Joshi Anjali, Tompkins Wayne A

Abstract excerpt

Feline Immunodeficiency Virus (FIV) is a lentivirus that causes immunodeficiency in cats, which parallels HIV-1-induced immunodeficiency in humans. It has been established that HIV envelope (Env) glycoprotein mediates T cell loss via a mechanism that requires CXCR4 binding. The Env glycoprotein of FIV, similar to HIV, requires CXCR4 binding for viral entry, as well as inducing membrane fusion leading to syncytia...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Benzylamines
Share to Cell Fusion
Share to Heterocyclic Compounds

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Immunodeficiency Virus, Feline

Share to Membrane Fusion

Share to Receptors, CXCR4

Share to Receptors, Tumor Necrosis Factor

Share to Viral Fusion Proteins

Source

Identifiers

PMID: 15567436
DOI: 10.1016/j.virol.2004.10.007

Genes

CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Feline immunodeficiency virus envelope glycoprotein mediates apoptosis in activated PBMC by a mechanism dependent on gp41 function.PMID 15567436Read ↗

HIV ENV glycoprotein-mediated bystander apoptosis depends on expression of the CCR5 co-receptor at the cell surface and ENV fusogenic activity.Semantic proximity Read ↗

Inhibition of Envelope-Mediated CD4<sup>+</sup>-T-Cell Depletion by Human Immunodeficiency Virus Attachment InhibitorsSemantic proximity Read ↗

Distinct mechanisms trigger apoptosis in human immunodeficiency virus type 1-infected and in uninfected bystander T lymphocytes.Semantic proximity Read ↗

Host and Viral Factors in HIV-Mediated Bystander ApoptosisSemantic proximity Read ↗

Altered bystander apoptosis induction and pathogenesis of enfuvirtide-resistant HIV type 1 Env mutants.Semantic proximity Read ↗

HIV-1 Env Glycoprotein Phenotype along with Immune Activation Determines CD4 T Cell Loss in HIV Patients.Semantic proximity Read ↗

Human Immunodeficiency Virus Type 1 Inhibits DNA Damage-Triggered Apoptosis by a Nef-Independent MechanismSemantic proximity Read ↗

Apoptosis is mediated by FeHV-1 through the intrinsic pathway and interacts with the autophagic processSemantic proximity Read ↗

Early Divergence in Neutrophil Apoptosis between Pathogenic and Nonpathogenic Simian Immunodeficiency Virus Infections of Nonhuman PrimatesSemantic proximity Read ↗

Spontaneous programmed cell death (PCD) process of lymphocytes of FIV-infected cats: cellular targets and modulation.Semantic proximity Read ↗

Genetic signatures of HIV-1 envelope-mediated bystander apoptosis.Semantic proximity Read ↗

Molecular determinants of acute single-cell lysis by human immunodeficiency virus type 1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.