Article
In vivo CXCR4 expression, lymphoid cell phenotype, and feline immunodeficiency virus infection.
Veterinary immunology and immunopathology - 15 May 2008
Troth Sean P, Dean Alan D, Hoover Edward A
Abstract excerpt
Primary isolates of feline immunodeficiency virus (FIV) appear to require binding to CD134 in conjunction with CXCR4(X4) to infect IL-2-dependent T-cell-derived cells in culture. However, much less is known about the role of X4 for the infection of cells in vivo. To investigate the correlation between X4 expression and FIV infection in cats acutely infected with FIV-C-Pgmr we used high-speed...
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