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Article

A nonlethal rat parvovirus infection suppresses rat T lymphocyte effector functions.

Journal of immunology (Baltimore, Md. : 1950) - 15 Oct 1995

McKisic M D, Paturzo F X, Gaertner D J, Jacoby R O, Smith A L

Abstract excerpt

Inoculation of the UMass strain of rat virus (RV-UMass) into adult immunocompetent rats results in a prolonged subclinical infection that is resolved in 4 to 8 wk. Co-labeling studies, using in situ hybridization (ISH) and immunohistochemistry (IHC), confirmed that RV-UMass was lymphocytotropic and capable of infecting CD4+ and CD8+ T cells as well as B cells. ISH studies also revealed that virus replication was...

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PMID: 7561106

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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