Article
Growth hormone induction of hepatic serine protease inhibitor 2.1 transcription is mediated by a Stat5-related factor binding synergistically to two gamma-activated sites.
The Journal of biological chemistry - 20 Oct 1995
Bergad P L, Shih H M, Towle H C, Schwarzenberg S J, Berry S A
Abstract excerpt
A growth hormone (GH)-inducible nuclear factor (GHINF) from rat liver has been purified to near homogeneity. On SDS-polyacrylamide gel electrophoresis and UV-cross-linking, a major band of mass approximately 93 kDa and a minor band of approximately 70 kDa are detected in the purified fraction. DN...
Topics
- Animals
- Base Sequence
- DNA-Binding Proteins
- Growth Hormone
- Humans
- Interferon-gamma
- Liver
- Milk Proteins
- Molecular Sequence Data
- Mutation
- Nuclear Proteins
- Rats
- Rats, Sprague-Dawley
- STAT1 Transcription Factor
- STAT5 Transcription Factor