Article
HLA-B27 testing: A journey from flow cytometry to molecular subtyping.
Journal of clinical laboratory analysis - 1 Jun 2018
Chheda Pratiksha, Warghade Sandeep, Mathias Jyothi, Dama Tavisha, Matkar Sunmeet, Shah Nilesh, Bendre Rajesh
Abstract excerpt
BACKGROUND: Determination of HLA-B27 status plays an important role as adjuvant in suspected cases for diagnosis of Ankylosing Spondilytis (AS). Objectives of this study were to evaluate (i) flow cytometry method in comparison with DNA microarray for HLA-B27 typing and (ii) EUROArray HLA-B27 Direct assay for HLA-B27 allele detection along with discrimination of AS/non-AS subtypes in Indian population. METHODS: A...
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