Article
Silent genes in bacteria: the previously designated 'cryptic' ilvHI locus of 'Salmonella typhimurium LT2' is active in natural isolates.
FEMS microbiology letters - 1 Sept 1995
Burns D M, Burger M J, Beacham I R
Abstract excerpt
Gene ilvG in Escherichia coli K-12 and ilvI in 'Salmonella typhimurium LT2' (S. enterica serotype Typhimurium, strain LT2) are inactive due to frameshift or nonsense mutations, respectively. These inactive genes have been suggested to be part of 'cryptic' genetic systems which are defined as being of long-term regulatory and evolutionary significance. We have shown that the nonsense mutation in ilvI is present...
Topics
- Alleles
- Base Sequence
- DNA Primers
- DNA, Bacterial
- Escherichia coli
- Gene Expression
- Genes, Bacterial
- Molecular Sequence Data
- Mutation
- Salmonella typhimurium
- Sequence Homology, Nucleic Acid