Article
Characterization and evolution of Salmonella CRISPR-Cas systems.
Microbiology (Reading, England) - 1 Feb 2015
Shariat Nikki, Timme Ruth E, Pettengill James B, Barrangou Rodolphe, Dudley Edward G
Abstract excerpt
Prokaryotic CRISPR-Cas (clustered regularly interspaced short palindromic repeats and CRISPR-associated genes) systems provide adaptive immunity from invasive genetic elements and encompass three essential features: (i) cas genes, (ii) a CRISPR array composed of spacers and direct repeats and (iii) an AT-rich leader sequence upstream of the array. We performed in-depth sequence analysis of the CRISPR-Cas systems...
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