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Article

Genetic variability among archival cultures of Salmonella typhimurium.

FEMS microbiology letters - 30 May 2001

Edwards K, Linetsky I, Hueser C, Eisenstark A

Abstract excerpt

The existence in our laboratory of over 10000 Salmonella typhimurium LT2 cultures sealed in agar stab vials for 33-46 years offers an opportunity for evolutionary and mutational studies. In each of 77 vials examined, 10(3)-10(5) colony forming units per vial were recovered (less than 0.01% of the original population) even after decades of undisturbed storage. Considerable genetic variability was observed in these...

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PMID: 11377870
DOI: 10.1111/j.1574-6968.2001.tb10677.x

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