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Article

Identification and molecular analysis of two apoB gene mutations causing low plasma cholesterol levels.

Circulation - 15 Oct 1995

Welty F K, Ordovas J, Schaefer E J, Wilson P W, Young S G

Abstract excerpt

BACKGROUND: Familial hypobetalipoproteinemia (FHB) is an autosomal codominant disorder characterized by abnormally low plasma levels of apoB and LDL cholesterol. Heterozygotes for FHB almost always have plasma LDL cholesterol levels < 70 mg/dL and are asymptomatic. Because the low cholesterol levels may protect FHB heterozygotes from coronary heart disease, the mechanisms for FHB are of considerable interest....

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PMID: 7554178
DOI: 10.1161/01.cir.92.8.2036

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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