Article
Linkage of the athymic nude locus with the myeloperoxidase locus in the rat.
Pathology international - 1 Apr 1995
Murakumo Y, Takahashi M, Hayashi N, Taguchi M, Arakawa A, Sharma N, Sakata K, Saito M, Amo H, Katoh H
Abstract excerpt
In rats of the BUF/Mna strain epithelial thymoma development is regulated by a single autosomal susceptible gene, Tsr-1. In pre-thymoma stage, BUF/Mna rats have extremely large thymuses, when compared with those of other strains of rats. The large thymus size of this strain is contributed by a thymus-enlargement gene, Ten-1. On the other hand, reduced thymus size and suppression of thymoma development were found...
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