Article
Linkage of neutrophil response to a mutagen gene (Nrm-1) to the agouti locus in the rat.
Journal of immunogenetics - 1 Jan 2000
Stolc V
Abstract excerpt
The ACI or BDIV rats responded with decreased or increased neutrophil levels in blood after the N-methyl-N-nitrosourea (MNU) administration. The F1 hybrids had decreased neutrophil counts, and the BDIV x (BDIV x ACI)F1 backcross offspring showed two phenotypes. The sex of the rats and the neutrophil response to MNU assorted independently. The results indicated that the neutrophil response to MNU was regulated by...
Topics
- Alleles
- Animals
- Crosses, Genetic
- Female
- Genes
- Genetic Linkage
- Leukocyte Count
- Male
- Methylnitrosourea
- Mutagens
- Neutrophils
- Phenotype
- Rats
