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Article

Identification of a naturally processed HLA-DR-restricted T-helper epitope in Epstein-Barr virus nuclear antigen type 1.

Journal of immunotherapy (Hagerstown, Md. : 1997) - 1 Jan 2000

Krüger Stefan, Schroers Roland, Rooney Cliona M, Gahn Benedikt, Chen Si-Yi

Abstract excerpt

Epstein-Barr virus nuclear antigen type 1 (EBNA1), the only viral protein that is unequivocally expressed in all Epstein-Barr virus (EBV)-associated malignant diseases, is essential for viral DNA replication and maintenance of the viral episome in infected cells. A glycine-alanine repeat domain inhibits antigen processing through the ubiquitin-proteasome pathway for presentation on human leukocyte antigen (HLA)...

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Source

Identifiers

PMID: 12806275
DOI: 10.1097/00002371-200305000-00005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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