Article
Functional differences and interactions between phenotypic subpopulations of olfactory ensheathing cells in promoting CNS axonal regeneration.
Glia - 1 Apr 2005
Kumar Rohan, Hayat Shaista, Felts Paul, Bunting Stephen, Wigley Caroline
Abstract excerpt
We demonstrate that there are significantly more p75 neurotrophin receptor- (NTR)-expressing cells in olfactory ensheathing cell (OEC) primary cultures from olfactory nerve rootlets (ONR), but a greater proportion of O4 antigen- and PSA-NCAM-expressing cells in parallel cultures from the nerve fibre layer of the olfactory bulb (OB). By co-culturing adult rat retinal ganglion cells (RGCs) with OECs derived from...
Topics
- Animals
- Antigens, Differentiation
- Brain Tissue Transplantation
- Cell Communication
- Cell Culture Techniques
- Cell Differentiation
- Cells, Cultured
- Coculture Techniques
- GTP-Binding Proteins
- Glial Fibrillary Acidic Protein
- Growth Cones
- Nerve Regeneration
- Neural Cell Adhesion Molecule L1