Article
Antigenic and sequence variation in the C-terminal unique domain of the Epstein-Barr virus nuclear antigen EBNA-1.
Virology - 20 Apr 1995
Wrightham M N, Stewart J P, Janjua N J, Pepper S D, Sample C, Rooney C M, Arrand J R
Abstract excerpt
The Epstein-Barr virus (EBV) nuclear antigen EBNA-1 is essential for viral genome maintenance in vitro and may be the only EBV protein expressed by the majority of latently infected cells in vivo. EBNA-1 may therefore be critical to the evasion of host immunity which allows persistent infection....
Topics
- Amino Acid Sequence
- Antibodies, Monoclonal
- Antibodies, Viral
- Antigenic Variation
- Antigens, Viral
- B-Lymphocytes
- Base Sequence
- Cell Line, Transformed
- DNA, Viral
- DNA-Binding Proteins
- Epitopes
- Epstein-Barr Virus Nuclear Antigens