Article
Rapid selection of cell subpopulation-specific human monoclonal antibodies from a synthetic phage antibody library.
25 Apr 1995
Abstract excerpt
Peripheral blood leukocytes incubated with a semisynthetic phage antibody library and fluorochrome-labeled CD3 and CD20 antibodies were used to isolate human single-chain Fv antibodies specific for subsets of blood leukocytes by flow cytometry. Isolated phage antibodies showed exclusive binding to the subpopulation used for selection or displayed additional binding to a restricted population of other cells in the...
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