Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Suppression of a cold-sensitive mutation in 16S rRNA by overexpression of a novel ribosome-binding factor, RbfA.

Genes & development - 1 Mar 1995

Dammel C S, Noller H F

Abstract excerpt

A novel 15-kDa protein, RbfA, has been identified by virtue of its ability to act as a high copy suppressor of a previously characterized dominant cold-sensitive mutation (C23U) in 16S rRNA. RbfA is found associated with free 30S ribosomal subunits, but not with 70S ribosomes or polysomes, and is essential for maximal cell growth, particularly at low temperatures. Cells lacking RbfA in a wild-type rRNA background...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Base Sequence
Share to Chromosome Mapping

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Escherichia coli

Share to Genes, Bacterial

Share to Genetic Complementation Test

Share to Molecular Sequence Data

Share to Phenotype

Source

Identifiers

PMID: 7535280
DOI: 10.1101/gad.9.5.626

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Suppression of a cold-sensitive mutation in 16S rRNA by overexpression of a novel ribosome-binding factor, RbfA.PMID 7535280Read ↗

The role of RbfA in 16S rRNA processing and cell growth at low temperature in Escherichia coli.Semantic proximity Read ↗

Mutations of ribosomal protein S5 suppress a defect in late-30S ribosomal subunit biogenesis caused by lack of the RbfA biogenesis factor.Semantic proximity Read ↗

Era and RbfA have overlapping function in ribosome biogenesis in Escherichia coli.Semantic proximity Read ↗

Suppression of defective ribosome assembly in a rbfA deletion mutant by overexpression of Era, an essential GTPase in Escherichia coli.Semantic proximity Read ↗

RBF1, a plant homolog of the bacterial ribosome-binding factor RbfA, acts in processing of the chloroplast 16S ribosomal RNA.Semantic proximity Read ↗

Cellular and molecular phenotypes depending upon the RNA repair system RtcAB of Escherichia coli.Semantic proximity Read ↗

A family of RRM-1 RNA binding proteins enables cold adaptation and environmental resilience in <i>Bacteroides</i>Semantic proximity Read ↗

RsgA releases RbfA from 30S ribosome during a late stage of ribosome biosynthesis.Semantic proximity Read ↗

Suppression of a cold-sensitive mutation in ribosomal protein S5 reveals a role for RimJ in ribosome biogenesis.Semantic proximity Read ↗

The ribosome assembly gene network is controlled by the feedback regulation of transcription elongation.Semantic proximity Read ↗

The YrdC protein--a putative ribosome maturation factor.Semantic proximity Read ↗

Mutations in 16S rRNA that suppress cold-sensitive initiation factor 1 affect ribosomal subunit association.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.